I-Retatrutide 5mg 10mg ixabiso eliphantsi
Igama lemveliso: Retatrutide
Inkcazo: 5mg * 10vial / kit 10mg * 10vials/kit
MOQ:1 kit
Ixabiso: 5mg USD320/kit 10mg USD600/kit
Indawo yemvelaphi: eTshayina
I-Retatrutide
I-Retatrutide (LY-3437943) iphantsi kophuhliso lonyango lwe-2 yesifo sikashukela, i-apnea ephazamisayo yokulala, i-osteoarthritis, ukukhuluphala kunye nesifo esingenasifo sesibindi esinamafutha.Umviwa wechiza ulawulwa ngendlela engaphantsi kwesikhumba kunye ne-intravenous.Umviwa weziyobisi wenza ngokujolisa kwi-glucagon-like peptide 1 (GLP-1), i-insulinotropic polypeptide exhomekeke kwi-glucose (GIP), kunye ne-glucagon receptors.Liqumrhu elitsha lemolekyuli.
I-Retatrutide isebenza kunyango lokutyeba ngokujolisa kwiihomoni ezintathu ezahlukeneyo ezilawula indlala: - I-GIP (i-gastric inhibitory peptide okanye i-glucose-dependent insulinotropic polypeptide) yi-hormone ye-incretin ekhutshwa emathunjini emva kokutya.I-Retatrutide ivuselela i-beta-cells kwi-pancreas ukuba ikhuphe i-insulin.Ichiza yi-peptide kunye nokulandelelana kwe-amino acid.I-agonist ye-hormone receptor kathathu ye-GLP-1, i-GIP, kunye ne-GCGR receptors.Kuye kwaboniswa ukuphumeza ngaphezu kwe-24% kuthetha ukunciphisa umzimba kubantu abangenasifo seswekile okanye abantu abadala.
I-Retatrutide iyafana ne-Ozempic, i-Wegovy, kunye ne-Mounjaro kuba sisitofu esikanye ngeveki se-hormone esitshintsha indlela esitya ngayo, ekhokelela kwiimvakalelo zokuqala zokuhlutha kunye nokunciphisa ukutya.
Kodwa ngokungafaniyo ne-Ozempic kunye ne-Wegovy, elinganisa ihomoni enye kuphela elawula indlala (GLP-1), okanye i-Mounjaro, elinganisa iihomoni ezimbini (i-GLP-1 kunye ne-GIP),retatrutideyimolekyuli enye elinganisa iihomoni ezintathu ezahlukeneyo ezilawula indlala: GLP-1, GIP, kunye neglucagon.Eso senzo “sikaGqu-ntathu,” njengoko ezinye izazinzulu zasibiza njalo entlanganisweni, sibonakala sinempembelelo enamandla ngakumbi kumnqweno womntu wokutya nokwaneliseka kukutya.
Kulingo olupapashwe kwi-NEJM, izigulana ezityebe kakhulu ezinikwe elona thamo liphezulu levekiretatrutide(12 mg) ulahlekelwe umyinge we-58 pounds kwiinyanga ze-11.Ubunzima babo babusehla naxa ulingo lwaphelayo, ecebisa ukuba amalingo amade, amakhulu angekagqitywa anokuzisa iziphumo ezinomtsalane ngakumbi zokwehla kobunzima.Isigulane ngasinye kwi-dose ephezulu ye-retatrutide ilahlekelwe ubuncinane i-5% yobunzima bomzimba wabo, kwaye ikota yalabo bathathi-nxaxheba balahlekelwa yi-30% okanye ngaphezulu kobunzima babo.
Kuphononongo olufanayo lwe-retatrutide kwizigulane ezine-Type 2 yeswekile epapashwe kwi-Lancet, abaguli balahlekelwe malunga ne-17% yobunzima bomzimba wabo kwiinyanga ezilithoba, into ephawulekayo, kuba ngokuqhelekileyo kunzima kwizigulane ezine-T2D ukuba zilahlekelwe ngumlinganiselo ofanayo wobunzima. njengabanye abantu abatyebe kakhulu kunye nokutyeba.
PHAWULA
Sithumela kwihlabathi liphela.
Uyacetyiswa ukuba udibane neengcebiso zakho zonyango ngaphambi kokusetyenziswa kwemveliso.