China Supply Sarms Raw Sr9009 Stenabolic API

I-REV-ERBα kunye ne-REV-ERBβ i-nuclear receptors zi-transcriptional repressors ezilungelelanisa isigqi se-circadian kunye neendlela ze-metabolic ngendlela exhomekeke kwi-heme.I-SR9009 i-agonist ye-REV-ERB eyandisa ukunyanzeliswa kwe-genesis elawulwa yi-REV-ERBα kunye ne-REV-ERBβ kunye ne-IC50 ixabiso le-670 kunye ne-800 nM, ngokulandelanayo.1Ngokusebenza kwe-REV-ERB, i-SR9009 ibonakaliswe ukunciphisa umsebenzi we-circadian locomotor ngexesha lobumnyama kunye nokuguqula ipateni yokubonakalisa i-core clock genes kwi-hypothalami yeempuku.1Ipatheni ye-circadian yokubonakalisa uluhlu lwezakhi ze-metabolic kwisibindi, i-skeletal muscle kunye nezicubu ze-adipose nazo zibonakaliswe ukuba zitshintshwe kwiigundane ezivezwe kwi-SR9009, okubangelwa ukunyuka kwenkcitho yamandla. I-SR9009 (i-ip kabini ngosuku ngeentsuku ze-30) ziye zabikwa ukuba zibonise ukuncipha kwamafutha kunye nokuphucula ngokuphawulekayo i-dyslipidemia kunye ne-hyperglycemia.1

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