Unyango lwe-TB-500 peptide: ukusetyenziswa, umthamo, kunye nokhuseleko

Inkxaso: Ukuba ungumphandi ojonge ukufaka i-TB-500 kumsebenzi wakho, esi sikhokelo siya kukunika ulwazi lwamva nje malunga ne-TB-500′s indlela yokwenza, ukusetyenziswa, kunye neziphumo ebezingalindelekanga.

I-TB-500 yinguqulelo eyenziwe ngokwendalo ye-peptide thymosin beta-4, aka timbetasin.Uphando nge-TB-500 ludla ngokubhekisa kuyo njenge-synthetic thymosin beta-4.

Izifundo zabantu kwi-TB-500 zinqongophele, kodwa i-peptide yinto yophando olusebenzayo ngenxa yeempawu zokuvuselela i-thymosin beta-4.

I-Thymosin beta-4 ifumaneka kwiseli nganye emzimbeni womntu ngaphandle kwe-erythrocytes, kwaye kucingelwa ukuba idlala indima kwi-angiogenesis, ukuphiliswa kwenxeba, kunye nokwanda kweeseli, ukwahlula kunye nokufuduka.

Ukuba ungumphandi ojonge ukudibanisa i-TB-500 kumsebenzi wakho, esi sikhokelo siya kukunika ulwazi lwamva nje malunga ne-TB-500′s indlela yokwenza, ukusetyenziswa, kunye neziphumo ebezingalindelekanga.

Sikwabandakanya iinkcukacha malunga nendlela yokwenza ithamo kunye nokulawula i-TB-500 kwizicwangciso zophando, kunye nalapho unokufumana khona i-99% yobunyulu be-TB-500 kwi-intanethi.

PS: Oda i-TB-500 kwi-intanethi apha!

Yintoni i-TB-500?

I-TB-500 luhlobo lokwenziwa lwe-thymosin beta-4 (TB4), i-peptide yomntu engapheliyo eyenziwe ngama-amino acids angama-43 kwaye inokufumaneka phantse kuzo zonke iiseli zomzimba, ngakumbi kwiiplatelets kunye neeseli ezimhlophe zegazi [1].I-TB4 yaqala ukubekwa yodwa ngo-1981 ngu-Low kunye ne-Goldstein kwisicatshulwa se-bovine thymus gland [2].

I-synthetic version, i-TB-500, ayizange ivunywe ukuba isetyenziswe ngabantu kwaye ifumaneka kuphela njengekhemikhali yophando.Yaqala ukwenziwa ekuqaleni koo-2010 ukuze isetyenziswe kunyango lwezilwanyana.I-TB-500 isetyenziswe njenge-agent ye-doping kumdyarho wamahashe kwaye yavalwa ngokulandelelana ukubonelela ngenzuzo engafanelekanga kulo mdlalo [3, 4].

I-Thymosin beta-4 kunye ne-derivatives yayo, kuquka i-TB-500, ngokufanayo ivalwe yi-World Anti-Doping Agency (WADA) kwaye ngenxa yoko inqatshelwe ukusetyenziswa ngabadlali abakhuphisanayo ngokuxhomekeke kwiKhowudi ye-WADA kunye nemibutho yolawulo yelizwe kunye neyengingqi efanayo [5].

I-TB-500 nangona kunjalo iphantsi kophando olusebenzayo malunga nemiphumo enokubakho ekufudukeni kweeseli kunye nokulungiswa kwezicubu, ukubunjwa kwemithambo yegazi emitsha, ukuvuthwa kweeseli ze-stem, ukusinda kweentlobo ezahlukeneyo zeeseli, kunye nesenzo esichasayo [1, 6].

I-TB-500 kunye ne-thymosin beta-4 zine-bioavailability yomlomo engafanelekanga, kwaye ngoko inokulawulwa kuphela ngeenaliti kwizicwangciso zokulinga.

Nangona kunjalo, iqhekeza elenzeka ngokwendalo le-thymosin beta-4, ebizwa ngokuba yi-N-acetyl seryl-aspartyl-lysyl-proline (Ac-SDKP), yipeptide esebenza ngomlomo ecinga ukuba ne-antifibrotic efanayo, i-anti-inflammatory, iipropathi ze-angiogenic, kunye neziphumo kwi. ukufuduka kweeseli kunye nokuphila [7, 8].

Kuye kwaphandwa njenge-inhibitor ye-hematopoietic stem cell proliferation kunye ne-agent chemoprotective [9, 10].Abaphandi banokufumana isiqwenga se-TB-500 esibandakanyiweyo kwiifomyula ze-capsule ze-TB-500 ezilungiselelwe ukulungiswa nokubuyiselwa kwezicubu.

TB-500 Dosage Calculator kunye neTshati

Kufanelekile ukuqaphela ukuba ngenxa yokunqongophala kophando olupapashiweyo kwi-TB-500, okwangoku akukho zindululo ezithile zedosi ngeenjongo zophando.

Uphando olukhoyo lubandakanya iimodeli zezilwanyana okanye izifundo zovavanyo, kwaye iziphumo zolu phando azikwazi ukusetyenziswa ngokuthe ngqo ebantwini.

Uphononongo lwabantu olulinganiselwe oluqhutywe nge-injection thymosin beta-4 ingxelo ye-TB-500 dosing eyahluka kakhulu kwaye ilawulwe ngexesha eliphezulu leentsuku ze-14.Akukho zifundo zonyango ezibandakanya iikhosi zonyango ze-TB-500 ze-peptide ezinde kuneeveki ezimbini [29, 30].

Ngenye indlela, i-thymosin beta-4 isetyenziswe ngokufanelekileyo kwizilingo zeklinikhi kwi-concentration ye-0.03% ngaphezu kweenyanga ezintathu.Ukusetyenziswa kwemixholo kukwabonise ukhuseleko olugqwesileyo kunye nokunyamezela [20].

Ngokusekwe kulwazi lwangoku, inaliti ye-TB-500 yokubuyisela ukwenzakala inokulawulwa ngokusekwe kule shedyuli ilandelayo:

• I-TB-500 I-Daily Dose: 2mg, ilawulwa ngaphantsi kwe-subcutaneously
• Ubude besifundo: Iintsuku ezili-15
• Amanqaku: Iibhotile ezintathu ze-TB-500 10mg ziyafuneka ukuze kugqitywe le protocol.Ukulandela ixesha leeveki ezimbini, abaphandi banokuqhubeka nokulawula i-dose yokugcinwa kwemihla ngemihla ye-1mg, njengoko kuyimfuneko, ukuphumeza ukubuyiswa ngokupheleleyo okanye kufutshane.

Ngolwazi oluthe vetshe malunga ne-TB-500 dosing, bona iinkcukacha zethuTB-500 Dosage Calculator kunye neTshati.

Ungayithenga phi i-TB-500 kwi-Intanethi?

Niniukuthenga i-TB-500 kwi-intanethingeenjongo zophando, abathengi bepeptide kufuneka bavavanye ngenyameko abathengisi abohlukeneyo ngokubhekiselele kumaxabiso, ukuthembeka, uphononongo lwabathengi, umgangatho wemveliso, iindlela zokuhlawula ezamkelweyo, kunye nenqanaba lenkonzo yabathengi ebonelelwayo.

Ngokusekelwe kumava ethu abanzi, sivuma ngentliziyo iphela iPeptide Sciences njengomthombo othembekileyo wophando lwebakala le-TB-500.Irekhodi yabo yokusoloko behambisa iimveliso ezisemgangathweni ibenza babe lolona khetho lubalaseleyo kubaphandi abafuna i-TB-500 kwi-intanethi.

Ukufumana i-TB-500 yebakala lophando lwenaliti, ndwendwela umthengisi wethu ozikhethelayo kubaphandi abaphambili kwihlabathi liphela.